Burning Thigh Pain (Meralgia Paresthetica) A painful, burning sensation on the outer side of the thigh may mean that one of the large sensory nerves to your legs—the lateral femoral cutaneous nerve (LFCN)—is being compressed. This condition is known as meralgia paresthetica (me-ral'-gee-a par-es-thet'-i-ka). The nerves in your body bring information to the brain about the environment (sensory nerves) and messages from the brain to activate muscles (motor nerves). To do this, nerves must pass over, under, around, and through your joints, bones, and muscles. Usually, there is enough room to permit easy passage. In meralgia paresthetica, swelling, trauma, or pressure can narrow these openings and squeeze the nerve. When this happens, pain, paralysis, or other dysfunction may result. Symptoms Pain on the outer side of the thigh, occasionally extending to the outer side of the knee A burning sensation, tingling, or numbness in the same area Occasionally, aching in the groin area or pain spreading across the buttocks Usually only on one side of the body Usually more sensitive to light touch than to firm pressure Examination During the appointment, your doctor will ask about recent surgeries, injury to the hip, or repetitive activities that could irritate the nerve. If your doctor suspects meralgia paresthetica, he or she will ask questions to help determine what might be putting pressure on the nerve. Restrictive clothing and weight gain are two of the more common causes of pressure. Your doctor may ask if you consistently wear tight stockings or a girdle, or whether you wear a heavy tool belt at work. In addition, meralgia paresthetica may result from a seatbelt injury during a car collision. Physical Examination Your doctor will also check for any sensory differences between the affected leg and your other leg. To verify the site of the burning pain, he or she will put some pressure on the nerve to reproduce the sensation. You may need both an abdominal and a pelvic examination to exclude any problems in those areas. Tests X-rays will help identify any bone abnormalities that might be putting pressure on the nerve. If your doctor suspects that a growth such as a tumor is the source of the pressure, he or she may ask for a magnetic resonance image or a computed tomography (CT) scan. In rare cases, a nerve conduction study may be advised. Treatment Treatments will vary, depending on the source of the pressure. The goal is to remove the cause of the compression. This may mean resting from an aggravating activity, losing weight, wearing loose clothing, or using a toolbox instead of wearing a tool belt. It may take time for the burning pain to stop and, in some cases, numbness will persist despite treatment. In more severe cases, your doctor may give you an injection of a corticosteroid preparation to reduce inflammation. This generally relieves the symptoms for some time. In rare cases, surgery is needed to release the nerve.